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  • Title: Human leukocyte antigens -A, -B, -C, and -DR and nasopharyngeal carcinoma in northern China.
    Author: Zhu XN, Chen R, Kong FH, Liu W.
    Journal: Ann Otol Rhinol Laryngol; 1990 Apr; 99(4 Pt 1):286-7. PubMed ID: 2327697.
    Abstract:
    We observed HLA associations in patients with nasopharyngeal carcinoma from northern China. There was an increased risk of nasopharyngeal carcinoma associated with HLA-B35 and a difference in the HLA association between patients with early- and late-onset disease. The frequency of B35 was significantly higher in patients than in control subjects, especially in early-onset patients (less than 30 years old). Late-onset patients had a higher frequency of DR2 as compared with normal subjects.
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