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  • Title: Cyclodextrin-modified micellar electrokinetic chromatography for enantioseparations.
    Author: Ibrahim WA, Hermawan D, Sanagi MM.
    Journal: Methods Mol Biol; 2013; 970():349-61. PubMed ID: 23283789.
    Abstract:
    The separation of enantiomers is one of the important fields of modern analytical chemistry, especially for agrochemical and pharmaceutical products because the stereochemistry has a significant influence on the biological activities of compounds. Cyclodextrin-modified micellar electrokinetic chromatography (CD-MEKC) has become an important capillary electrophoresis mode for enantioseparations. Here, we describe an example of a CD-MEKC method using hydroxypropyl-γ-cyclodextrin as chiral selector and sodium dodecyl sulfate as micellar solution for enantioseparation of triazole fungicides and the drug econazole.
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