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  • Title: Naltrexone for treatment of acral lick dermatitis in dogs.
    Author: White SD.
    Journal: J Am Vet Med Assoc; 1990 Apr 01; 196(7):1073-6. PubMed ID: 2329076.
    Abstract:
    Acral lick dermatitis (lick granuloma) was diagnosed in 11 dogs on the basis of history, physical examination, and histopathologic findings. A predilection for the left forelimb was noticed. All 11 dogs were given the narcotic antagonist naltrexone. Successful treatment (cessation of licking, reepithelialization of lesions) was seen in 7 dogs. All 7 dogs' lesions recurred when naltrexone was stopped, but reepithelialized in 5 dogs when the drug was readministered. Adverse effects (drowsiness, withdrawal from owner) were seen in 1 dog, but resolved within 48 hours of stopping the drug.
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