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  • Title: Role of nitric oxide-detoxifying enzymes in the virulence of Pseudomonas aeruginosa against the silkworm, Bombyx mori.
    Author: Arai H, Iiyama K.
    Journal: Biosci Biotechnol Biochem; 2013; 77(1):198-200. PubMed ID: 23291757.
    Abstract:
    Pseudomonas aeruginosa has two nitric oxide (NO)-detoxification enzymes, NO reductase and flavohemoglobin, which catalyze the reduction and oxygenation of NO respectively. In this study, the NO reductase-deficient mutant showed decreased virulence against the silkworm Bombyx mori, but the flavohemoglobin-deficient mutant did not, indicating that NO-reduction is important to the full virulence of P. aeruginosa against B. mori.
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