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  • Title: How accurate is CBCT in measuring bone density? A comparative CBCT-CT in vitro study.
    Author: Cassetta M, Stefanelli LV, Pacifici A, Pacifici L, Barbato E.
    Journal: Clin Implant Dent Relat Res; 2014 Aug; 16(4):471-8. PubMed ID: 23294461.
    Abstract:
    PURPOSE: Recently, cone beam computed tomography (CBCT) has become widely used for oral and maxillofacial imaging. Twenty dry mandibles were CBCT and conventional multislice CT scanned to evaluate if there is a statistically significant difference between the bone density values they produce, defined as gray density values, and to determine any correlation between them. MATERIALS AND METHODS: Using software and a radiographic template, the CT and CBCT scan images were overlapped, and two data sets were created, each one giving the respective gray values (voxel value [VV] or Hounsfield unit [HU]) of the same area with the same spatial coordinates. For the statistical analysis, t-test, Pearson's correlation, and Pearson's r were used. RESULTS: The differences between the CBCT (VV) and CT (HU) gray density values were statistically significant (p ≤ .05), whereas the Pearson's correlation coefficients and Pearson's r-values demonstrated a statistically significant linear correlation between VV and HU gray density values. CONCLUSION: The lower radiation dose and reduced costs of CBCT make this a useful substitute for CT; however, this study has shown that, in order to more accurately define the bone density with CBCT, a conversion ratio needs to be applied to the VV.
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