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  • Title: 1H NMR detection of small molecules in human urine with a deep cavitand synthetic receptor.
    Author: Ryan DA, Rebek J.
    Journal: Analyst; 2013 Feb 21; 138(4):1008-10. PubMed ID: 23304698.
    Abstract:
    A water-soluble deep cavitand recognized alkylammonium salts, including the drug amantadine hydrochloride, in spiked samples of human urine. The signals of the guests are detected by (1)H NMR upfield of 0 ppm and so occur in a spectroscopic window that is outside of the normal region and distinct from the signals of the biofluid components.
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