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  • Title: Direct lactonization of 2-arylacetic acids through Pd(II)-catalyzed C-H activation/C-O formation.
    Author: Yang M, Jiang X, Shi WJ, Zhu QL, Shi ZJ.
    Journal: Org Lett; 2013 Feb 01; 15(3):690-3. PubMed ID: 23320461.
    Abstract:
    Palladium-catalyzed direct lactonization of 2-arylacetic acids through a reaction sequence that includes C-H activation/C-O formation is reported. This method provides a concise and efficient pathway to synthesize fully functionalized benzofuranone derivatives, which are highly relevant to bioactive natural and synthetic products.
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