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  • Title: Clinical remission following plasmapheresis and corticosteroid treatment in a dog with acquired myasthenia gravis.
    Author: Bartges JW, Klausner JS, Bostwick EF, Hakala JE, Lennon VA.
    Journal: J Am Vet Med Assoc; 1990 Apr 15; 196(8):1276-8. PubMed ID: 2332375.
    Abstract:
    A 7-year-old sexually intact male Labrador Retriever with regurgitation and generalized muscular weakness resulting from acquired myasthenia gravis received 2 plasmapheresis treatments in combination with corticosteroid treatment. Plasmapheresis was performed in an attempt to rapidly lower serum acetylcholine receptor binding antibody (AChR Ab) concentration. Seven days after the second plasmapheresis treatment, the dog's muscular strength was normal, which coincided with a 70% decrease in serum AChR Ab concentration. Because the dog also received corticosteroids, it is impossible to determine how much of the clinical improvement resulted from plasmapheresis.
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