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  • Title: [Initial experiences with "Oranienburg" slow-release theophylline in asthma therapy of children and adolescents].
    Author: Sollich V, Schuster R, Thal W, Köhler E, Walther H.
    Journal: Kinderarztl Prax; 1990 Jan; 58(1):45-8. PubMed ID: 2332947.
    Abstract:
    Experiences in 50 patients show that Theophyllin retard Oranienburg (280 mg theophylline) could be used as an effective bronchospasmolytic drug on conditions of mono- and combination-therapy. Advantages of this preparation are improvement of the compliance and an undisturbed night-sleep in patients. However an optimum dosage is hardly maintained in children by the present dose of a single tablet of 280 theophylline content. The effectiveness in therapy of childhood asthma could be improved by stronger sustained release effect and different doses of tablets.
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