These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Preoperative platelet-lymphocyte ratio is an independent prognostic factor for resectable colorectal cancer].
    Author: Liu H, DU X, Sun P, Xiao C, Xu Y, Li R.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2013 Jan; 33(1):70-3. PubMed ID: 23353160.
    Abstract:
    OBJECTIVE: To evaluate the impact of preoperative platelet-lymphocyte ratio (PLR) on the prognosis in patients with operable colorectal cancer. METHODS: The clinical data of 140 patients with operable colorectal cancer were analyzed retrospectively. According to preoperative PLR, the patients were divided into low PLR group (PLR<250) and high PLR group (PLR≥250). The overall 5-year survival rates and the clinicopathological factors in the two groups were analyzed using univariate analysis and COX regression model. RESULTS: The patients with a high PLR had a significantly lower overall 5-year survival rate than those with a low PLR (71.4% vs 51.5%, P=0.045). Univariate analyses identified tumor location, the depth of tumor invasion, lymph nodes metastasis, TMN stage, and PLR as significant risk factors for reduced overall 5-year survival. In COX regression model, a high PLR was identified as an independent risk factor for poorer prognosis in patients with resectable colorectal cancer (RR: 2.213; 95%CI: 1.007-4.863, P=0.0048). CONCLUSION: Preoperative PLR can be a clinically significant factor for assessment of prognosis of resectable colorectal cancer.
    [Abstract] [Full Text] [Related] [New Search]