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  • Title: A case of secundum atrial septal defect combined with aortic stenosis and coronary artery disease showing a single second heart sound.
    Author: Saitoh M, Miyakoda H, Fukuki M, Yamasaki J, Fujimoto Y, Hasegawa J, Kotake H, Mashiba H.
    Journal: Jpn Heart J; 1990 Jan; 31(1):121-6. PubMed ID: 2335843.
    Abstract:
    We describe an extremely rare case of secundum atrial septal defect with aortic stenosis and coronary artery disease showing a single second heart sound throughout the respiratory cycle by echocardiogram with simultaneous phonocardiogram. Aortic valve closure corresponded to the single second heart sound. We were unable to detect pulmonary valve closure (PVC) on echocardiogram. Because of the presence of pulmonary hypertension, the pulmonary component of the second heart sound (P2) was presumed to be increased in intensity, and the PVC-P2 interval was thought to be abbreviated. Carotid pulse tracing showed a prolongation of the left ventricular ejection time. We concluded that the single second heart sound was due to both prolongation of left ventricular systole and pulmonary hypertension.
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