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  • Title: Skin conductance reflects drug-induced changes in blood levels of cortisol, adrenaline and noradrenaline in dogs.
    Author: Ishibashi M, Akiyoshi H, Iseri T, Ohashi F.
    Journal: J Vet Med Sci; 2013; 75(6):809-13. PubMed ID: 23358494.
    Abstract:
    To verify availability of skin conductance (SC) as an indicator for the sympathetic nervous system (SNS) activity in dogs, the changes in SC and blood levels of stress-related hormones induced by drugs were compared. SC and cortisol, adrenaline and noradrenaline levels were measured in 5 dogs on 4 occasions with or without drug-induced sedation at 7-day intervals (no treatment, intramuscular medetomidine 0.01 mg/kg, intramuscular acepromazine 0.1 mg/kg and intravenous fentanyl 0.02 mg/kg). The fentanyl treatment produced significantly higher levels of SC and plasma cortisol and adrenaline compared with the other 3 treatments. The plasma noradrenaline level also tended to be higher following the fentanyl treatment. These results indicate that SC may reflect changes in the SNS activities in dogs.
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