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  • Title: [Determination of effective renal blood flow and the rate of glomerular filtration by sequential administration of I-131 hippuran and Yb-169 DTPA].
    Author: Kasatkin IuN, Shliakhto EV, Dolgova IB, Karpikov RI, Pushkarev AA.
    Journal: Med Radiol (Mosk); 1990 Apr; 35(4):46-8. PubMed ID: 2336013.
    Abstract:
    The authors present the results of the determination of the effective renal blood flow (ERB), the effective renal plasma flow (ERP) and the rate of glomerular filtration (GRF) by sequential administration of 131I-hippuran and 169Yb-DTPK assessing the contribution of each radionuclide in blood plasma specimens with the help of a multichannel pulse analyzer. The mean values of ERB (738.4 +/- 27.3 ml/min), ERP (391 +/- 22.4 ml/min) and GRF (128.9 ml/min) were in full accord with the literature data. The difference between GRF values calculated in the presence of 131I in plasma and after its decomposition, did not exceed 5% (6.4 +/- 1.8 ml/min), and the ratio of correlation between them was 0.948, p less than 0.01. A possibility of simultaneous determination of ERB and GRF under clinical conditions was shown.
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