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  • Title: [The blood rheological properties in suppurative-septic urologic diseases and their correction by plasmapheresis].
    Author: Kozlov VA, Aleksandrova NP, Gladshteĭn MD, Gushchin BL.
    Journal: Urol Nefrol (Mosk); 1990; (1):3-7. PubMed ID: 2336754.
    Abstract:
    A total of 18 patients with pyoseptic urological diseases (the main group) treated with plasmapheresis and 18 patients who were not (the control group) were studied for certain rheological parameters: platelet and red cell aggregation, number of platelets, hematocrit, ESR, viscosity values of the blood with a shift rate of 9 and 105 s-1 and osmotic resistance of red cells. 18 patients were exposed to 26 plasmapheresis sessions with a plasma removal of 3-3.2% of the body weight. Significant disorders of blood rheology: higher platelet ad red cell aggregation, lower erythrocyte osmotic resistance and increased blood viscosity were revealed in patients with pyoseptic urological diseases. In case plasmapheresis was included into the complex treatment, in line with the clinical efficacy of the latter a rapid normalization of the aforementioned parameters was documented by the 3-7th day of the treatment. Uroseptic patients who were exposed to plasmapheresis demonstrated improved microcirculation confirmed by isotope renography and Bengal rose which identified the improved performance of the kidneys and the liver. With account for the beneficial effect of plasmapheresis on hemorheological values in uroseptic patients, the authors suggested that for septic patients plasmapheresis substitution type should be changed.
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