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  • Title: Langerhans cell histiocytosis: a diagnostic dilemma.
    Author: Ryan PL, Piper KM, Hughes FJ.
    Journal: Dent Update; 2012 Dec; 39(10):716-8, 720. PubMed ID: 23367637.
    Abstract:
    UNLABELLED: Langerhans cell histiocytosis (LCH) is a rare clonal neoplastic disorder of unknown aetiology which can present with a diverse range of clinical presentations. It encompasses a diverse number of idiopathic conditions which can involve multiple body systems and is characterized by bone marrow-derived Langerhans cell proliferation. The disease can affect multiple body systems and lesions can be solitary or widespread. We present a case of a multifocal eosinophilic granuloma (LCH) in a young adult female with clinical signs and symptoms similar to aggressive periodontitis. CLINICAL RELEVANCE: Langerhans cell histiocytosis is a rare disease which can have a similar clinical presentation to aggressive periodontitis.
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