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  • Title: [Aggressive debridement and early soft tissue coverage of 3d degree open tibial fractures].
    Author: Ketterl RL, Steinau HU, Feller AM, Stübinger B, Claudi BF.
    Journal: Zentralbl Chir; 1990; 115(4):209-18. PubMed ID: 2336882.
    Abstract:
    93 patients with grade III open tibial fractures were treated without a treatment protocol from 1980 to 1982. This group is compared to 147 pts. managed between 1983 to 1986 according to a standardized prospectively designed protocol with aggressive debridement augmented by pulsatile Jet-lavage. Serial debridement were performed at 48-hour intervales until early soft-tissue coverage were obtained using local or free muscle-flaps. The mean follow-up was 80 months respectively 44 months. --The aggressive regimen led to a statistically significant decrease in infection (30% vs 12%), nonunion (16% vs 6%), amputation (18% vs 6%) and combined hospitalization-periods (137 vs 74 days) [all p less than 0.001]. The aggressively treated groups showed a trend toward early fracture-healing (30 vs 23 weeks) although this was not statistically significant.
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