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  • Title: Synthesis and pharmacological properties of 2-nitro-3-substituted-amino benzo[b]thiophenes and 1-substituted benzothieno[2,3-d]imidazoles.
    Author: Guerrera F, Salerno L, Siracusa MA, Ronsisvalle G, Caruso A, Leone MG, Felice A.
    Journal: Farmaco; 1990 Jan; 45(1):29-38. PubMed ID: 2337445.
    Abstract:
    The synthesis of 1-substituted benzothieno[2,3-d]imidazoles and their most suitable synthesis precursor 2-nitro-3-substituted-amino benzo[b]thiophenes is reported. Most of these latter compounds show analgesic and antiinflammatory activities sometimes comparable to those of phenylbutazone with less toxicity and gastric lesivity.
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