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  • Title: Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus.
    Author: Bahnous M, Bouraiou A, Chelghoum M, Bouacida S, Roisnel T, Smati F, Bentchouala C, Gros PC, Belfaitah A.
    Journal: Bioorg Med Chem Lett; 2013 Mar 01; 23(5):1274-8. PubMed ID: 23374871.
    Abstract:
    Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.
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