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  • Title: Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp.
    Author: Contino M, Zinzi L, Perrone MG, Leopoldo M, Berardi F, Perrone R, Colabufo NA.
    Journal: Bioorg Med Chem Lett; 2013 Mar 01; 23(5):1370-4. PubMed ID: 23374872.
    Abstract:
    Compounds 8a-d have been designed as bioisosters of tariquidar for imaging P-gp expression and density by PET. The results displayed that compounds 8b and 8d could be considered potential P-gp/BCRP ligands suitable as (11)C and (18)F radiotracers, respectively.
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