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  • Title: Management of the contralateral testis in patients with testicular germ cell cancer.
    Author: Fordham MV, Mason MD, Blackmore C, Hendry WF, Horwich A.
    Journal: Br J Urol; 1990 Mar; 65(3):290-3. PubMed ID: 2337749.
    Abstract:
    Patients with testicular germ cell tumours (TGCT) are at increased risk of developing a tumour in the contralateral testis. Such a tumour may be preceded by carcinoma in situ (CIS), which is more common in patients with infertility, atrophic testis or a history of cryptorchism. Of 1219 patients with TGCT seen at the Royal Marsden Hospital between 1962 and 1984 in whom the contralateral testis was managed by surveillance, 38 (3.1%) developed a second tumour and 8 died of germ cell tumours. Seventeen of 26 assessable patients (65%) exhibited at least one of the known aetiological risk factors for carcinoma in situ. Diagnosis of carcinoma in situ may lead to more appropriate management of the contralateral testis.
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