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Title: Placental CSF-like activity. Author: Meagher R, Amsden A, Hunt J, Soares M, Sogor L, Smith RN. Journal: Exp Hematol; 1990 Jun; 18(5):448-51. PubMed ID: 2338133. Abstract: We have examined amniotic fluid and cultured supernatants of a variety of placental cells for the presence of colony-stimulating factor (CSF) activity. The supernatants of cultured human choriocarcinoma cell lines, Jeg and Jar, contained CSF activity that induced the formation of granulocyte-macrophage colony-forming unit (CFU-GM) and multipotential colony-forming unit (CFU-GEMM) colonies. Cultured supernatants of nontransformed rat placental cells, chorionic villous cells, and amniotic fluid also induced CFU-GM colonies.[Abstract] [Full Text] [Related] [New Search]