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  • Title: Small cell neuroendocrine tumor of the larynx--a small case series.
    Author: Mikić A, Zvrko E, Trivić A, Stefanović D, Golubović M.
    Journal: Coll Antropol; 2012 Nov; 36 Suppl 2():201-4. PubMed ID: 23397787.
    Abstract:
    Neuroendocrine tumors are the most common nonsquamous types of laryngeal neoplasms. They are classified as typical carcinoids, atypical carcinoids, small-cell neuroendocrine carcinomas, and paragangliomas. The aim of the paper is to present four patients with small-cell neuroendocrine tumor arising in larynx. There were one woman and three men whose ages were 47-77 years; all of them had metastases when first seen. The clinical presentation and management of such type of tumor are discussed. Small-cell neuroendocrine carcinomas are very aggressive neoplasms. Patients could benefit from surgery, but radiotherapy and chemotherapy remain the treatment of choice. Examination of a large series is required to define the most useful diagnostic methods and the most successful treatment modalities.
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