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  • Title: Twin pregnancies: evaluation of major depression, stress, and social support.
    Author: Benute GR, Nozzella DC, Prohaska C, Liao A, de Lucia MC, Zugaib M.
    Journal: Twin Res Hum Genet; 2013 Apr; 16(2):629-33. PubMed ID: 23398666.
    Abstract:
    BACKGROUND: Twin pregnancies are at increased physiological and psychosocial risks. OBJECTIVE: To investigate the prevalence of major depression in twin pregnancies and correlate with stress and social support. METHOD: The study included 51 pregnant women under specialized prenatal care who were evaluated by a Portuguese version of the semi-structured questionnaire Primary Care Evaluation of Mental Disorders (PRIME-MD) for Major Depression, and the Prenatal Psychosocial Profile (PPP) for evaluation of stress and social support. RESULTS: Major depression was found in 33.3% of pregnant women, and prevailing symptoms were fatigue or loss of energy (100%), insomnia or hypersomnia (82.4%), changes in appetite (82.4%), decreased interest in daily activities (82.4%), and psychomotor agitation or retardation (82.4%). Among pregnant women who were diagnosed depressive, 76.5% also had a high level of stress and 47.1% complained about lack of social support. Statistical significance was found when correlating depression with perception of negative aspects of having twins and belief in significant body changes during pregnancy (p = .005 and .03, respectively). Marital status, occupation, and pregnancy planning were not significantly associated with the diagnosis of depression. CONCLUSION: Major depression occurs in one-third of pregnant women expecting twins and is associated with higher levels of stress and lack of social support. A multidisciplinary approach in these cases is fundamental to minimize further risks and complications.
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