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  • Title: Antiplaque activity of some antimicrobial agents using a simple in vitro method.
    Author: Murata Y, Miyamoto E, Ueda M.
    Journal: Caries Res; 1990; 24(2):113-6. PubMed ID: 2340540.
    Abstract:
    Some antimicrobial compounds were tested for their antiplaque activity by a simple method involving measurement of the weight of Streptococcus sobrinus plaque on a glass surface. Chlorhexidine, cetylpyridinium chloride, and n-tetradecylamine reduced the weight of plaque produced by S. sobrinus in vitro; some N-palmityl and palmitoyl derivatives of polymethylenediamines were also found to possess antiplaque activity. The results suggest that an antiplaque effect does not necessarily depend on high bactericidal activity.
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