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  • Title: High selectivity imaging of nitroreductase using a near-infrared fluorescence probe in hypoxic tumor.
    Author: Xu K, Wang F, Pan X, Liu R, Ma J, Kong F, Tang B.
    Journal: Chem Commun (Camb); 2013 Mar 28; 49(25):2554-6. PubMed ID: 23423494.
    Abstract:
    A highly selective and sensitive near-infrared (NIR) fluorescence probe (Cy-NO2) for imaging nitroreductase was developed and was successfully applied to investigating the relationship between epithelial-mesenchymal transitions (EMTs) in tumour progression and intracellular hypoxic level.
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