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  • Title: [Design and evaluation of DAVIH VIH-2].
    Author: Martín Alfonso D, Silva Cabrera E, Pérez Guevara MT, Díaz Herrera DF, Romero Martínez K, Díaz Torres HM, Lubián Caballero AL, Ruiz Gutiérrez N, Ortiz Losada E.
    Journal: Rev Cubana Med Trop; 2007; 59(3):241-6. PubMed ID: 23427463.
    Abstract:
    The results of the design and evaluation of DAVIH VIH-2 diagnosing system, an indirect Elisa for screening of HIV-2 antibodies, which uses a HIV-2 glycoprotein gp36 synthetic peptide in its solid phase, were exposed. In the system evaluation using WHO reference panels, 100% sensitivity, 99,81% specificity, 99,81% efficacy and very good concordance level (kappa = 0.978) were attained. Serum samples of 959 individuals with undetermined or negative results to the HIV-1 antibodies confirmation (DAVIH blot) were evaluated by the DAVIH VIH-2 system. Twenty four samples were reactive, six of which had confirmed HIV-2 antibodies. These results allowed recommending the introduction of this diagnostic kit in the HIV infection diagnosing algorithm in Cuba.
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