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  • Title: Vacuole sign and nodule sign in early peripheral bronchogenic carcinoma. Diagnostic value and pathologic correlation.
    Author: Yang XM, Hu MH, Xie YC, Yan HZ, Liu HR, Wang DT, Stark P.
    Journal: Radiologe; 1990 Apr; 30(4):169-71. PubMed ID: 2343101.
    Abstract:
    We analyzed the radiological and pathological characteristics of 30 peripheral lung masses 1.5-3 cm in diameter. We describe the vacuole and the nodule sign. Retrospective examination of 100 conventional tomograms of peripheral pulmonary masses and comparison with the histological diagnoses allowed us to determine the usefulness of these two signs in differentiating small peripheral bronchogenic carcinomas from tuberculomas.
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