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  • Title: Genetic variation and biochemical properties of esterase-18 (ES-18) in the laboratory rat (Rattus norvegicus): a new locus of esterase cluster 2 in linkage group V.
    Author: Kluge R, Hedrich HJ, von Deimling O.
    Journal: Biochem Genet; 1990 Feb; 28(1-2):57-68. PubMed ID: 2344348.
    Abstract:
    A new liver-specific rat carboxylesterase isozyme (EC 3.1.1.1) designated esterase-18 (ES-18) is described. Genetic variation of ES-18 was examined in 93 inbred strains and substrains and a structural locus Es-18 was suggested, coding for either the presence (Es-18a) or the absence (Es-18b) of the isozyme. Linkage studies involving two backcross series revealed that Es-18 resides in cluster 2 of LGV. No recombination between Es-18 and other cluster 2 loci was found in 19 lines of two RI strain sets or in the backcross series.
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