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  • Title: Necrotic hepatocellular carcinoma occurring within an inflammatory pseudotumor-like nodule.
    Author: Takahashi Y, Iwata J, Shima Y, Sumiyoshi T, Kozuki A, Ishibashi A, Takao T, Yamamoto M, Yamamoto M.
    Journal: Intern Med; 2013; 52(5):551-4. PubMed ID: 23448763.
    Abstract:
    Hepatocellular carcinoma (HCC) and inflammatory pseudotumor of the liver (IPL) are often difficult to differentiate before surgery. To date, colocalization of IPL and HCC has not been reported. We experienced a case of necrotic HCC surrounded by IPL-like tissue. The raised levels of alpha-fetoprotein and PIVKA-II declined to within the normal ranges after resection of the tumor. The IPL-like nodule most likely developed as a process of an inflammatory reaction such as abscess formation after the spontaneous destruction of the HCC. Our case is a warning that the presence of a 'pseudotumor' does not rule out the possible simultaneous presence of carcinoma.
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