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  • Title: Primary papillary carcinoma of the thyroid arising in a branchial cyst: case report and review of the literature.
    Author: Gollahalli PK, Chikkannaiah P, Annam V.
    Journal: Ear Nose Throat J; 2013 Feb; 92(2):E3-5. PubMed ID: 23460225.
    Abstract:
    We report a case of papillary carcinoma of the thyroid that arose in a branchial cyst. The patient, a 45-year-old woman, presented with a left lateral neck mass of 3 months' duration. The cyst was removed intact. Because we could not rule out the possibility that a small primary malignancy was present within the gland, we performed a total thyroidectomy; however, no occult primary tumor of the thyroid was found. The patient was placed on thyroid hormone replacement therapy, and she was well at 2 years of follow-up. We briefly review the literature regarding the possible embryologic origin of such a phenomenon and the role of fine-needle aspiration cytology in differentiating a branchial cyst from a metastatic lymph node. To the best of our knowledge, this is only the 11th reported case of a thyroid papillary carcinoma arising in ectopic thyroid tissue within a branchial cyst, and the second such report from India.
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