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  • Title: Regular paracetamol in severe dengue: a lethal combination?
    Author: Gan CS, Chong SY, Lum LC, Lee WS.
    Journal: Singapore Med J; 2013 Feb; 54(2):e35-7. PubMed ID: 23462840.
    Abstract:
    An eight-month-old female infant with severe dengue disease, who was repeatedly given therapeutic paracetamol for severe dengue, developed fulminant liver failure with encephalopathy, gastrointestinal haemorrhage and severe coagulopathy. She responded to supportive measures and N-acetylcysteine infusion. This case highlights the potential danger of administering repeated therapeutic doses of paracetamol in childhood severe dengue disease with hepatitis.
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