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  • Title: R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes.
    Author: Rønne M, Kirpekar F, Shibasaki Y, Poulsen BS, Kristiansen K.
    Journal: Anticancer Res; 1990; 10(2A):375-7. PubMed ID: 2346311.
    Abstract:
    A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.
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