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  • Title: Liver plasma membrane proteins in chronic ethanol intoxication.
    Author: Babu PP, Vemuri MC.
    Journal: Biochem Int; 1990; 20(3):573-7. PubMed ID: 2346500.
    Abstract:
    Plasma membrane proteins were isolated from control and ethanol-treated rat livers by the use of two-dimensional gel electrophoresis (IEF-SDS-PAGE). Two groups of proteins differing in their response to ethanol were analysed and termed as ethanol-sensitive proteins (ESP) and ethanol insensitive proteins (EISP). This study indicates a loss of many membrane-associated proteins and strongly suggests a role for these proteins in the mechanism of plasma membrane disruption by ethanol.
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