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  • Title: Blue rubber-bleb naevus syndrome: report of a case with consumption coagulopathy complicated by manifest thrombosis.
    Author: Hofhuis WJ, Oranje AP, Bouquet J, Sinaasappel M.
    Journal: Eur J Pediatr; 1990 May; 149(8):526-8. PubMed ID: 2347349.
    Abstract:
    Blue rubber-bleb naevus (BRBN) syndrome is a rare disorder characterized by subcutaneous and gastrointestinal haemangiomas. The latter may lead to bleeding complications. A case is reported in which a process of chronic intravascular coagulation resulted in serious thrombotic complications. In the presence of a chronic consumption coagulopathy, it remains uncertain whether antiplatelet drugs are of prophylactic antithrombotic value.
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