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  • Title: Successful treatment of Kasabach-Merritt syndrome with transarterial embolization and corticosteroids.
    Author: Zhou SY, Li HB, Mao YM, Liu PY, Zhang J.
    Journal: J Pediatr Surg; 2013 Mar; 48(3):673-6. PubMed ID: 23480932.
    Abstract:
    Kasabach-Merritt syndrome (KMS) refers to the combination of large neonatal vascular tumors and thrombocytopenic coagulopathy. However, a standard treatment regimen for KMS has not yet been established. We report a case of a 6-week-old male infant with life-threatening KMS who was successfully treated with transarterial embolization and corticosteroids. One week after initiating the corticosteroid treatment, his platelet counts recovered, and the lesion growth halted. The approach with corticosteroid therapy resulted in an excellent response that was maintained long enough for us to perform transarterial embolization therapy. The combination of transarterial embolization and corticosteroid therapy should be considered as an option for Kasabach-Merritt syndrome.
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