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Title: Aphanamgrandiol A, a new triterpenoid with a unique carbon skeleton from Aphanamixis grandifolia. Author: Zeng Q, Guan B, Ren J, Wang CH, Cheng XR, Qin JJ, Yan SK, Jin HZ, Zhang WD. Journal: Fitoterapia; 2013 Apr; 86():217-21. PubMed ID: 23481281. Abstract: Aphanamgrandiol A (1), a novel triterpenoid with a bicyclo[3,2,1]octane ring skeleton produced by 2,3-ring opening and 2,6-ring closure, was isolated from the stems of Aphanamixis grandifolia. The structures were established on the basis of extensive spectroscopic methods, including 1D and 2D NMR techniques, and determined unambiguously by X-ray crystal diffraction. Aphanamgrandiol A showed moderate cytotoxicities against MCG-803, SKOV-3, HCT116 and HepG2 cell lines.[Abstract] [Full Text] [Related] [New Search]