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  • Title: [Cellular immunity in actively conditioned recipients of renal allotransplants (author's transl)].
    Author: Haefen UV, Garovoy MR, Wren SF, Martins AC, Wilson RE.
    Journal: Dtsch Med Wochenschr; 1975 Feb 21; 100(8):370-2. PubMed ID: 234839.
    Abstract:
    The presence of circulating "killer" cells was demonstrated in actively "conditioned" rats with permanently accepted renal allotransplants. Immunocompetant cells of these animals were able to develop a normal graft-versus-host reaction 100 and 200 days after the transplantation. The ability of these recipients simultaneously to accept secondary donor-specific skin transplants without demonstrable immunological rejection is compatible with the concept that the cytotoxic potential of these cells in vivo is inhibited by enhancing antibodies.
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