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  • Title: [A polypoidal adenosquamous cell carcinoma of the esophagus with a pseudosarcomatous stromal reaction].
    Author: Tanimura A, Yatsuka K, Sakai R, Tachibana K, Noda S.
    Journal: Gan No Rinsho; 1990 May; 36(6):728-32. PubMed ID: 2348561.
    Abstract:
    A case of a polypoidal carcinoma with a pseudosarcomatous stromal reaction is presented. Histologically, the polypoidal tumor of the lower esophagus was revealed to be an adenosquamous cell carcinoma associated with the proliferation of atypical stromal cells, osteoclastic-like giant cells, and histiocytes. Using an immunohistochemical stain, these stromal atypical cells were found to be positive for vimentin, with some cells positive for alpha 1-antichymotrypsin. However these atypical cells proved negative as epithelial markers (keratin and EMA). Thus, it was felt that such atypical stromal cells may be a reactive proliferation of the stromal cells to an adenosquamous cell carcinoma.
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