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  • Title: Effect of p-chloromercuribenzene sulfonate on gastric parietal and surface cell function in the dog.
    Author: Moody FG, Simons M, Jackson T.
    Journal: Gastroenterology; 1975 Feb; 68(2):279-84. PubMed ID: 234902.
    Abstract:
    p-Chloromercuribenzene sulfonate, a polar organic mercurial which presumably penetrates cell membranes with great difficulty, led to a profound decrease in acid recovered from exteriorized segments of dog gastric fundus stimulated by exogenous histamine. Trapping of secreted hydrogen ions by Tris buffer did not significantly reduce the back-diffusion component of apparent inhibition. Sodium-for-hydrogen exchange was close to unity before and after inhibition.
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