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  • Title: A case of rapidly progressive, fatal mycosis fungoides presenting as a haematoma-like lesion.
    Author: Hattori T, Uchiyama A, Tago O, Nagai Y, Ishikawa O.
    Journal: Acta Derm Venereol; 2013 Nov; 93(6):707-10. PubMed ID: 23493993.
    Abstract:
    Mycosis fungoides usually follows an indolent clinical course. We report here a rapidly progressive case of mycosis fungoides with peculiar clinical and histological features, presenting as a haematoma-like mass on the thigh accompanied by multiple reddish brown erythematous lesions on the trunk and extremities. Histopathologically, the erythematous lesions showed epidermotropism of atypical T lymphocytes expressing CD4 and prominent syringotropism without syringometaplasia. The haematoma-like lesion consisted of diffuse and dense infiltrates of medium-to-large-sized pleomorphic lymphocytic cells expressing CD30, suggesting that CD30+ large-cell transformation had occurred. Mycosis fungoides presenting as a haematoma-like lesion is rare and may be a poor prognostic sign.
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