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  • Title: HTRF(®): pioneering technology for high-throughput screening.
    Author: Degorce F.
    Journal: Expert Opin Drug Discov; 2006 Dec; 1(7):753-64. PubMed ID: 23495998.
    Abstract:
    Cisbio international pioneered the field of homogeneous fluorescence methodologies and time-resolved fluorescence resonance in particular, through its proprietary technology, HTRF(®). The development was based on Prof. Jean-Marie Lehn's research on rare earth fluorescence properties (awarded the Nobel Prize in Chemistry in 1987) and on Cisbio's expertise in homogenous time-resolved fluorescence (HTRF). The technology is used in assay development and drug screening, most notably in high-throughput screening applications. This highly powerful technology is particularly applied to the areas of G-protein-coupled receptor and kinase screening, as well as a series of targets related to inflammation, metabolic diseases and CNS disorders.
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