These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Modulation of the antibiotic activity by extracts from Amburana cearensis A. C. Smith and Anadenanthera macrocarpa (Benth.) Brenan.
    Author: Figueredo FG, Ferreira EO, Lucena BF, Torres CM, Lucetti DL, Lucetti EC, Silva JM, Santos FA, Medeiros CR, Oliveira GM, Colares AV, Costa JG, Coutinho HD, Menezes IR, Silva JC, Kerntopf MR, Figueiredo PR, Matias EF.
    Journal: Biomed Res Int; 2013; 2013():640682. PubMed ID: 23509756.
    Abstract:
    The aim of this study was to verify the possible interactions between ethanol extracts of Amburana cearensis A. C. Smith and Anadenanthera macrocarpa (Benth.) Brenan, combined with six antimicrobial drugs against multiresistant strains of Staphylococcus aureus and Escherichia coli isolated from humans. The antibacterial activity of the extracts was determined using the minimum inhibitory concentration (MIC). The microdilution assay was performed to verify the interactions between the natural products and the antibiotics using a subinhibitory concentration. The activity of amikacin associated with the extract of Anadenanthera macrocarpa against EC 27 was enhanced, demonstrating an MIC reduction from 128 to 4  μg/mL. Among the β-lactams, no potentiation on its activity was observed, with exception to the antagonism of the natural products with ampicillin against S. aureus 358.
    [Abstract] [Full Text] [Related] [New Search]