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  • Title: Castleman's disease in the orbit of a 17-year-old girl: a case report.
    Author: Jones NW, Fountain TR, Thakral B, Eldibany M.
    Journal: Ophthalmic Plast Reconstr Surg; 2014; 30(1):e17-20. PubMed ID: 23512000.
    Abstract:
    Castleman's disease is an atypical lympho proliferative disorder comprising hyaline vascular elements, plasma cells, or a mixture of both, which can present in unicentric or multicentric fashion. Resection of unicentric lesions is typically curative, but multicentric disease, also characterized by constitutional symptoms and a poorer prognosis, often requires treatment with chemotherapy, radiation, steroids, or immune modulators. Castleman's disease is rarely diagnosed in the orbit. The authors present the clinical and histopathological findings of a 17-year-old who was found to have a focal lesion in her orbit. She was successfully treated with surgical resection and was free of disease recurrence or other sequelae at 10-months follow up.
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