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  • Title: Synthesis and hepatitis C antiviral activity of 1-aminobenzyl-1H-indazole-3-carboxamide analogues.
    Author: Shi JJ, Ji FH, He PL, Yang YX, Tang W, Zuo JP, Li YC.
    Journal: ChemMedChem; 2013 May; 8(5):722-5. PubMed ID: 23512654.
    Abstract:
    FIGHTING HCV: Two potent antiviral analogues were developed from a previously identified lead as novel agents against hepatitis C virus. Their potency and selectivity (5 n: IC50 =0.013 μM and EC50 =0.018 μM; 5 t: IC50 =0.007 μM and EC50 =0.024 μM) make them good candidates for further development as antiviral agents.
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