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  • Title: Decreasing Clostridium difficile infections in surgery: impact of a practice bundle incorporating a resident rounding protocol.
    Author: Bishop J, Parry MF, Hall T.
    Journal: Conn Med; 2013 Feb; 77(2):69-75. PubMed ID: 23513633.
    Abstract:
    INTRODUCTION: Clostridium difficile (CD) infection is a significant health problem. A new systems approach was introduced to reduce the risk of hospital-acquired CD infection (HA-CD) at our institution. We hypothesized that a practice bundle, including a protocol to limit patient exposures during house staff rounding, would decrease HA-CD infections. METHODS: Over a three-year period, 39,093 cases (17,145 inpatients) admitted to the surgical services were reviewed. Cases were reviewed for patient demographics, antibiotic exposures, compliance with antibiotic prophylaxis guidelines, and surgical infections. A resident rounding protocol was developed to limit patient exposures. The program bundle also included a hand washing initiative, maintaining gastric acidity, and antibiotic stewardship. RESULTS: After implementation of the bundle, the average monthly HA-CD infection rate in surgical patients decreased from 4.13 + 2.6 cases to 1.93 + 1.6 cases, p = 0.03. The overall rate of HA-CD infections for surgical cases decreased 41% from 2.8 cases/1,000 patient days to 1.8 cases/1,000 patient-days. CONCLUSIONS: Bundled programs designed to reduce patient risk by controlling exposure to both environmental and carrier sources of CD can reduce hospital-acquired CD infections.
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