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  • Title: Increased serum kininase I activity in pregnancy complicated by pre-eclampsia.
    Author: Ito Y, Mizutani S, Nomura S, Kurauchi O, Kasugai M, Narita O, Tomoda Y.
    Journal: Horm Metab Res; 1990 Apr; 22(4):252-5. PubMed ID: 2351375.
    Abstract:
    Serum kininase I activity was measured in normal pregnancy and pre-eclampsia. The mean value in nonpregnant controls was 180 +/- 25 (SD) nmol/min/ml. Kininase I activity during normal pregnancy significantly increased after week 14, reaching the highest value (240 +/- 20 nmol/min/ml) at weeks 38 and 40. The kininase I activity in pregnancy complicated by severe pre-eclampsia was higher than that in normal pregnancy. The possible role played by elevated kininase I levels in pre-eclampsia was discussed.
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