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  • Title: [Update on current care guidelines: multiple sclerosis].
    Journal: Duodecim; 2013; 129(5):548-9. PubMed ID: 23520898.
    Abstract:
    Treatment for relapsing-remitting multiple sclerosis (RRMS) is initiated upon fulfillment of new McDonald 2010 criteria for RRMS. Patients with clinically isolated syndrome and at high-risk for RRMS are followed by magnetic resonance imaging to confirm the diagnosis of RRMS as early as possible. Interferon-beta and glatiramer acetate are the first-line immunomodulating drugs (IMD) for RRMS. If the disease is active according to clinical or MRI evaluation during the first-line IMD treatment, fingolimod or natalizumab may be considered as second-line therapies. IMD is discontinued upon the transition of RRMS to secondary progressive phase.
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