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  • Title: T1 and T2 relaxation times on gadolinium-diethylenetriaminepentaacetic acid enhanced magnetic resonance images of brain tumors.
    Author: Yamada S, Kubota R, Yamada K, Ono S, Hishinuma T, Matsuzawa T, Fujiwara S.
    Journal: Tohoku J Exp Med; 1990 Feb; 160(2):145-8. PubMed ID: 2353348.
    Abstract:
    MRI of brain tumors was performed with CPMG pulse sequence, and T1 and T2 relaxation times were measured before and after the administration of 0.1 mmol/kg Gd-DTPA. T1 and T2 became significantly shorter than before with the T1 shortening being about twice the T2's. Three types of T2 shortening were classified by the difference in the intra-tumoral transport of Gd-DTPA in the time-course study after the administration. Transportal activity of Gd-DTPA seemed to be reflected by the physiologic viability of tumor suggested by pre-contrast T2.
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