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  • Title: Iodine absorption in burn patients treated topically with povidone-iodine.
    Author: Lavelle KJ, Doedens DJ, Kleit SA, Forney RB.
    Journal: Clin Pharmacol Ther; 1975 Mar; 17(3):355-62. PubMed ID: 235397.
    Abstract:
    Providone-iodine is used as a topical antimicrobial in burn patients. Although absorption of iodine has been thought to be negligible, several patients have recently been noted with substantial elevations of serum free iodide. Unexplained abnormalities occurred in several of these patients, renal failure, metabolic acidosis, and elevation of serum glutamic oxaloacetic transaminase. It is conceivable that the large iodide loads noted were at least in part responsible for these abnormalities.
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