These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Catalytic asymmetric synthesis of γ-butenolides by direct vinylogous reactions.
    Author: Yan L, Wu X, Liu H, Xie L, Jiang Z.
    Journal: Mini Rev Med Chem; 2013 May 01; 13(6):845-53. PubMed ID: 23544459.
    Abstract:
    The γ-butenolide structural motif is a prominent feature in many bioactive natural products and drugs. This short review summarizes catalytic asymmetric synthesis of γ-butenolides through direct vinylogous reactions by metal complexes and organocatalysts. In light of building chiral γ-tertiary and quaternary carbon centers of butenolides, three synthetic strategies are included: 1) the reactions with furanone derivatives as nucleophiles, 2) olefination of γ,γ- disubstituted butenolides and 3) the reactions by using γ,γ-disubstituted butenolides as nucleophiles.
    [Abstract] [Full Text] [Related] [New Search]